Chondroitin, main characteristics, contraindications and methods of use

condroitina solfato

In short.

What is chondroitin sulfate and what importance does it have for cartilage and joints. How to take it, dosages and contraindications

In detail we will talk about

What is chondroitin and how is it used in the world of supplementation. What are the potential side effects and contraindications

For the discomfort related to the joints it is possible to exploit the power of chondroitin, which we will describe better in this resource. In the in-depth study, all the most important notes regarding the composition and main characteristics of this molecule are found.

With the first part of the article, we will clarify the nature of the molecule and the most important uses in the context of integration . We will know the composition and the specific processes that regulate its functioning . Further on, we will also go into the topic relating to the specific location in nature of chondroitin. For ever more precise, but never verbose information, at the end of the article we will collect a series of the most important questions relating to chondroitin . Among others, important information regarding the dosage and methods of use .

What is chondroitin, what is it used for?

Certainly better known by the name of chondroitin sulphate which identifies this molecule in a more technical way. In fact, chondroitin is a molecule that comes from the family of glycosaminoglycans .

These are nothing more than combinations of disaccharide units which, perfectly aligned, form chains of alternating elements . In these chains there is a precise alternation between an aminosaccharide and a monosaccharide . Specifically, what is a chondroitin chain composed of?

It is an alternating series of sequences of sugars which, to be precise, are two:

  1. N-acetyl-D-galactosamine-4/6-sulfate;
  2. D-glucuronate.

These two different sugars, in fact, make up a chain of sequences that alternate and produce the chondroitin molecule. In our scientific “vocabulary” chondroitin has a particular affinity with calcium molecules. In fact, in our body, the chondroitin molecules are able to develop an excellent interaction with those of calcium.

This type of interaction is functional to the development of different types of chondroitin sulphate. The scientific knowledge accumulated to date has allowed us to identify 4 different types of chondroitin sulphate depending on the chemical properties and physical characteristics of the molecule . In particular, it was possible to identify, based on the activities of these different types of molecules.

Chondroiotin sulfate A, B, C, D, E

  • Chondroitin sulfate A : as well as glucosamine, this type of sulfate carries out its main action in cartilage tissues . Especially in the joints , creating that reactivity that allows the tissues to function in its protective activity between the bony ends of the joints;
  • Dermatan sulfate : renamed for some time, because previously it was simply known as chondroitin sulfate b. Wanting to analyze the main tasks, we can underline how this type of chondroitin is the one that manages to interact with a long series of different tissues . Among these, the most important are blood vessels , heart valves and skin ;
  • Chondroitin sulfate C, D, E : These elements should be inserted in the same point, as they are elements that often interact with bone structures .

What is chondroitin used for?

Like glucosamine, chondroitin also serves for the maintenance and general health of cartilage tissues . The action of chondroitin is able to mechanically affect the tissues. This type of interaction is capable of providing more than one support to the tissues.

The first task of chondroitin is to allow the action of the connective tissues in absorbing the liquids and water that we take daily . This action is essential to keep cartilage tissues healthy. To this type of action we must add another equally fundamental one.

To the support activity is added that of protecting the cartilage itself. This mechanism ends in stopping the activity of enzymes which with their action degrade the cartilage structures . Therefore, a multiplicity of tasks that do not end here, as regards chondroitin. Maintaining the conditions of elasticity and, therefore, the ability to reinforce the cartilage tissues and help them maintain their strength over time. Last but not least, the ability to limit the onset of inflammatory conditions . This is possible thanks to the efficacy demonstrated by chondroitin in limiting the production , and therefore the action, of the mediators to which the onset of inflammation can be attributed .

Chondroitin sulfate: recommended dosage

It is necessary to have a very clear picture regarding the dosage of chondroitin , especially in reference to the possibility of having to perform a glucosamine chondroitin sulfate dosage.

In fact, in many cases, the supplements for sale are made even more efficient thanks to the combination of these two molecules. Furthermore, the combination of further elements finds space in the treatments that require it. For example: glucosamine / chondroitin / hyaluronic acid.

A precise summary can be made in relation to the weight of the person who will have to follow the treatment. The doses vary precisely because of this factor. In general, a lower chondroitin sulfate dosage is recommended compared to using glucosamine .

A person weighing over 45kg should take 1200mg of chondroitin daily .

Instead, an individual weighing less than 45kg should limit themselves to taking about 800mg of chondroitin daily .

It remains to analyze the case of the subjects , large obese , who exceed a weight of 90 kg. People with these problems should, first of all, consult a specialist to understand what is the best way to approach the treatment .

Chondroitin: where is it found in nature?

Chondroitin is produced properly by certain animal tissues and it is not always easy to identify it in nature . At the human level, as previously pointed out, it can be identified in the cartilage tissues of the knees, or in the tendon structures.

As well as in humans, even in animals this is produced in specific anatomical areas which are the cartilaginous ones, such as in cows. In these, the area predisposed to production is easily identifiable in the trachea . There are also other animals with tissues that are generally rich in chondroitin . In sharks , for example, it is possible to identify more than one anatomical section rich in chondroitin. We are often asked about the possibility of finding a specific vegetable chondroitin, that is, that it is not extracted from animal tissue. It’s possible? Let’s go and see it in the next paragraph.

Vegetable chondroitin: does it really exist?

As complicated as it may seem to be believed, plant chondroitin is not easy to find, because this molecule is effective only on an animal level .

There are studies documenting some validity of fermented chondroitin products, but research is still far from finding a definitive answer. Supplements based on chondroitin sulfate are absolutely effective and effective and easily available in various online marketplaces.

Beneficial effects of chondroitin

Let’s talk in more detail about the use of chondroitin at the level of food supplementation. Today, supplements with chondroitin sulfate and glucosamine are available for the health and maintenance of cartilage structures .

The most effective are those that combine the action of different elements that contribute to supplement the diet of the athlete, but also of the person who is weak or deficient in joint health. What does a supplement generally contain that can provide a truly useful practical action? In this image, here are some important elements that a complete supplement must have.

Some beneficial effects that stand out from joint health alone should not be underestimated. We will take a look at these a little further on.

The main benefit of supplementing chondroitin sulfate in the diet is its ability to help alleviate inflammatory conditions of cartilage tissues such as those of the knee. Thanks to the intake of this element, together with glucosamine , there is a marked improvement in joint mobility.

Are there other pathological conditions that chondroitin sulfate is able to improve? If this is taken in combination with hyaluronic acid it is able to relieve inflammation in the urinary tract . In the case of interstitial cystitis , for example, it can help repair the structure of the urothelium tissue that helps make up the urethra.

One of the most recent principals in the use of chondroitin is that relating to the health of the joints of our 4-legged friends . Is it possible , for example, to use chondroitin for dogs? Let’s analyze this specific example.

Chondroitin for dogs: benefits

As with humans, dogs too often face joint problems due to the degeneration and malfunction of cartilage tissues. Is it possible to use supplements with chondroitin for dogs?

Under the advice of a veterinary expert, it is not certain that this molecule cannot be as effective as it does on humans. Let us take the classic hip dysplasia of animals in old age as a specific example.

Many experts have found optimal results by supplementing their normal diet with chondroitin sulfate . These are effects linked above all to the alleviation of pain that occurs following the wearing down of the cartilage. This translates into an effective improvement in the quality of life of the animal in old age .

Chondroitin for dogs: side effects

There are some warnings that must be kept in mind, especially regarding contraindications. In general, these are the same ones that can be found in humans .

What are the side effects of taking chondroitin sulfate supplements for animals? In the list we can include:

  • Nausea;
  • Stomach ache;
  • He retched;
  • Diarrhea;
  • Feeling of bloating.

A non-certified, but potentially effective way to avoid conditioning your dog’s day with one of these side effects is to take the supplement in combination with daily meals.

Chondroitin sulfate: contraindications and undesirable effects

The use of chondroitin-based food supplements must always be under the control of a specialist. Expert advice is essential in understanding the dosage and application of these aids.

Contraindications chondroitin sulfate

That said, it is imperative to state that supplements based on this molecule are really very safe . No particular adverse reactions have been reported to an adequate intake of this element. This means that, with a precise dosage and a respectful intake of the quantities , in the ways and times, agreed with an expert, it will be difficult to present particular contraindications .

But what are the specific side effects that can occur if you are taking chondroitin? The most general ones are related to stomach problems , such as diarrhea and nausea , or a feeling of bloating . For this reason, it is advisable to take the supplement in close proximity to meals and never on an empty stomach .

Chondroitin sulfate: side effects

Research is still trying to fully document the presence of side effects of chondroitin . Some studies have focused on certain effects, finding indicative answers about some of them. What are the main side effects of chondroitin? Among these we find problems for:

  1. Diabetics : especially for patients using chondroitin and glucosamine supplements, as these may play a role in increasing insulin resistance;
  2. Allergic to shellfish : in patients with shellfish allergies, some side effects may occur from taking chondroitin. In reality, a true link has not yet been proven, but this indication could come directly from a doctor as a precautionary measure;
  3. Who takes anticoagulants : the intake of chondroitin is absolutely not indicated in patients who are already taking anticoagulant medicines, due to the stimulus that this could have compared to accidental bleeding.

Let’s now take some ideas to understand more briefly the characteristics and action of chondroitin through what are the most sought-after questions on the net about it.

FAQ chondroitin sulfate

There are relatively few questions to which it is important to find an answer regarding chondroitin sulphate, but each of these is essential to better understand its action and functioning.

How does chondroitin work for cartilage?

Apparently, chondroitin is able to guarantee two beneficial effects on cartilage and their health. A first beneficial effect is that relating to the maintenance of the degree of efficiency of the cartilage tissues .

A second practical result is given by the effectiveness of this molecule to function as an anti- inflammatory . That is, it is able to limit pain in the joints, such as in the knee.

What are the contraindications of chondroitin sulfate?

Research, in this sense, is always in full swing and has served to demonstrate that, in the right dosage, chondroitin sulphate is safe for humans. The main contraindications are related to gastric problems such as nausea and vomiting , but also diarrhea and heartburn .

How is chondroitin used in the making of supplements?

In the context of supplementation, it is easy to find products that combine chondroitin sulfate and glucosamine. Apparently, the effectiveness of these two molecules together is much more efficient.

In even more specific products, it is possible to find the presence of hyaluronic acid, which represents an excellent boost for cartilage treatments. Remember that chondroitin, like glucosamine, can only be extracted from animal tissue.

Chondroitin sulfate, what are its properties?

We are faced with a molecule with different properties and potential yet to be fully studied. Its main property lies in its ability to be an excellent anti-inflammatory for cartilage structures.

This means that it can also have an effective action for joint pain conditions such as that of the knee. Among other properties, it also acts as an antidegenerative for cartilage tissues.

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